creation date: 2026-09-01 16:36
tags: Pathologies


Hypovolemic Shock

Background

Definitions

Shock is defined as a life-threatening condition of circulatory failure. It is a state of cellular tissue hypoxia due to inadequate oxygen delivery for the metabolic demands.

The effects of shock are initially reversible but can deteriorate to an irreversible state with multiorgan failure and death.

Four types of shock are recognized, of which multifactorial shock is possible. The specifics of each type are described in their respective pages:

The general approach to undifferentiated shock is described separately. This articles describes specific findings and treatment of this type of shock.

Etiology

Hypovolemia results from a loss of intravascular fluid causing decreased preload and stroke volume, thus decreased cardiac output.

Hemorrhagic

  • Shock due to a reduction in intravascular volume from blood loss
  • Can be due to blunt or penetrating trauma, upper, and lower GI bleed (in order of prevalence).
  • Less common causes include intra- and postoperative bleeding, ruptured aneurysm, and more

Non-hemorrhagic

  • Loss of fluid other than blood
  • Could be from GI (eg. diarrhea, vomitting), skin loss (eg. burns), renal loss (eg. salt-wasting nephropathies), or third space losses into extravascular space or body cavities

Risk Factors

  • Trauma
  • GI problems (eg. ulcer, bleed)
  • Surgery
  • Ectopic pregnancy
  • Burst aneurysm

Clinical Presentation

Signs & Symptoms

Vitals:

  • Tachycardia (may be normal on beta blocker)
  • Hypotension
  • Tachypnea (unless severe shock)
  • SpO2 usually normal (unless severe)
  • Decreased pulse pressure

Presents with characteristic reduced preload with suspected/known cause:

  • Reduced skin turgor
  • Dry mucous membranes
  • Collapsible IVC on imaging
  • Low CVP (<8 mmHg)
  • Orthostatic hypotension
  • Pallor
  • Flattened JVP
  • Sequelae of chronic liver disease

Findings may vary additionally based on hemorrhagic or nonhemorrhagic etiology.

History & Physical Exam

Diagnosis

Criteria

Shock is a clinical diagnosis.

Work-up

Differential

Red Flags / Complications

Management

References

Tools / Guidelines

Additional Reading