creation date: 2026-08-10 17:21
tags: Workups


Scrotal Mass

Background

Pathophysiology

Differential Diagnosis

Immediately emergent

Non-emergent

  • Epididymitis/epididymoorchitis
  • Apendage torsion
  • Incarcerated/strangulated inguinal hernia
  • Traumatic hematoma
  • Testicular cancer

Benign

  • Spermatocele / epididymal cyst
  • Hydrocele
  • Varicocele (may be concerning if right sided)

Initial Evaluation

History

History should include:

  • Onset and duration
  • Associated symptoms including pain
  • History of trauma, infection, surgery

History should rule out concerning features of testicular torsion. Suspicion of such should proceed accordingly.

Physical Exam

Physical exam consist of palpation of the scrotum. A systematic approach should be used to assess:

  • Scrotal fullness (size, “bag of worms”) - suggestive of varicocele
  • Unitlateral or bilateral diffuse swelling, uniform in consistency - hydrocele
  • Localized fullness at head of epididymis - epididymal cyst of spermatocele
  • FIrm, nontender nodule/mass on testis - testicular cancer
  • Mass in paratesticular tissue or tail in epididymis - adenomatoid tumour

Transillumination of the scrotum may be helpful (hydrocele permits transillumination).

Investigations

If the diagnosis is unclear from initial evaluation, a scrotal ultrasound should be performed. US is >95% sensitive for concerning intratesticular lesions, of which should be referred to urology.

References

Tools / Guidelines

Additional Reading