creation date: 2025-10-21 23:34
tags: PathologiesIncomplete
Ischemic Cardiomyopathy
Background
Definitions
Ischemic cardiomyopathy (ICM) refers to a heart muscle disease characterized by an impaired ability to pump blood properly due to myocardial damage from ischemia.
In most cases, ICM stems from coronary artery disease. Eventually, ICM will lead to heart failure.
Etiology and Pathogenesis
Coronary artery disease is the primary cause of ICM. The lack of sufficient blood supply results in cell death, fibrosis, left ventricular enlargement, and remodelling.
As the left ventricle becomes injured, its systolic function decreases and ejection fraction drops.